Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143425 | 0.98 | ALDH1A1 (0.50) | ALDH1A1TSHRGAAHPGDMAPK1 | |
| SCHEMBL1483113 | 0.80 | ALDH1A1 (0.52) | ALDH1A1GAAHPGDMAPK1MAPT | |
| SCHEMBL1598193 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL11305211 | 0.78 | ALDH1A1 (0.42) | ALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL472480 | 0.76 | ALDH1A1 (0.72) | ALDH1A1TSHRGAAHPGDMAPK1 | |
| Formaldehyde SCHEMBL8835715 | 0.74 | TSHR (0.44) | ALDH1A1TSHRGAAHPGDMAPT | |
| SCHEMBL17294189 | 0.74 | ALDH1A1 (0.69) | ALDH1A1TSHRGAAHPGDMAPK1 | |
| SCHEMBL6469814 | 0.73 | TSHR (0.35) | ALDH1A1TSHRGAAMAPTMEN1 | |
| SCHEMBL11494758 | 0.73 | GAA (0.38) | ALDH1A1TSHRGAAMAPTMEN1 | |
| SCHEMBL11883738 | 0.73 | TSHR (0.35) | ALDH1A1TSHRGAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121302-A | BROAD SPECTRUM PRESERVATIVE COMPRISING ISOTHIAZOLONES WITH ALKANOL-SUBSTITUTED DIMETHYLHYDANTOIN AS FORMALDEHYDE DONOR, AND AN ALKYL HYDANTOIN AS A STABILIZER FOR ISOTHIAZOLONE; LOW FREE FORMALDEHYDE, STABLE IN LARGE PH RANGE | LONZA, INC. (US) | 2000-09-19 | — | — | US | claimed |