Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722470 | 1.00 | NOTUM (0.36) | NOTUMALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL4722462 | 1.00 | NOTUM (0.36) | NOTUMALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL4722070 | 0.86 | P2RX7 (0.39) | NOTUMS1PR1 | |
| SCHEMBL4722067 | 0.86 | P2RX7 (0.39) | NOTUMS1PR1 | |
| SCHEMBL4722304 | 0.85 | NOTUM (0.36) | NOTUMALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL4723325 | 0.85 | NOTUM (0.36) | NOTUMALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL4722182 | 0.85 | NOTUM (0.36) | NOTUMALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL14102092 | 0.85 | PDK2 (0.34) | NOTUMMAPTKDM4EMAPK1HSD17B10 | |
| SCHEMBL4720700 | 0.85 | ITGB2 (0.39) | ACACB | |
| SCHEMBL4720703 | 0.85 | ITGB2 (0.39) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |