Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722070 | 1.00 | P2RX7 (0.39) | P2RX7PDE7AMCHR1HSD11B1F10 | |
| SCHEMBL14102092 | 0.91 | PDK2 (0.34) | NOTUMS1PR1 | |
| SCHEMBL14101726 | 0.88 | F2 (0.37) | P2RX7F10F2NOTUMS1PR1 | |
| SCHEMBL4720703 | 0.88 | ITGB2 (0.39) | ITGB2ICAM1ITGAL | |
| SCHEMBL4720700 | 0.88 | ITGB2 (0.39) | ITGB2ICAM1ITGAL | |
| SCHEMBL4718933 | 0.87 | P2RX7 (0.38) | P2RX7PDE7AMCHR1HSD11B1F10 | |
| SCHEMBL4718937 | 0.87 | P2RX7 (0.38) | P2RX7PDE7AMCHR1HSD11B1F10 | |
| SCHEMBL4724969 | 0.86 | NOTUM (0.36) | NOTUMS1PR1 | |
| SCHEMBL4722470 | 0.86 | NOTUM (0.36) | NOTUMS1PR1 | |
| SCHEMBL4722462 | 0.86 | NOTUM (0.36) | NOTUMS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |