Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724613 | 0.89 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4ENPSR1RXFP1 | |
| SCHEMBL4293962 | 0.89 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ENPSR1RXFP1 | |
| SCHEMBL4724931 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4ENPSR1RXFP1 | |
| SCHEMBL4724540 | 0.87 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ENPSR1RXFP1 | |
| SCHEMBL4291546 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ENPSR1RXFP1 | |
| SCHEMBL4764475 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4ENPSR1RXFP1 | |
| SCHEMBL4766111 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4ENPSR1RXFP1 | |
| SCHEMBL4287081 | 0.80 | ALDH1A1 (0.79) | ALDH1A1MAPTKDM4ERXFP1PKM | |
| SCHEMBL4287139 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4ERXFP1PKM | |
| SCHEMBL4762533 | 0.80 | RAB9A (0.61) | ALDH1A1MAPTKDM4ENPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971596-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | Takeda Pharmaceutical Company Limited (JP) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007077961-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-12 | — | — | WO | disclosed |