Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725923 | 0.93 | NR4A2 (0.57) | NR4A2MAOBRAB9ANPC1MRGPRX4 | |
| SCHEMBL4779408 | 0.91 | FFAR1 (0.48) | NR4A2MAOBRAB9ANPC1MRGPRX4 | |
| SCHEMBL4726535 | 0.84 | FFAR1 (0.46) | NR4A2MAOBRAB9ANPC1MAPT | |
| SCHEMBL4257586 | 0.80 | AKR1C3 (0.49) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL27555763 | 0.79 | TDP1 (0.56) | NR4A2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL4726534 | 0.78 | PTGER1 (0.52) | RAB9ANPC1KMT2ALMNAMEN1 | |
| SCHEMBL5090803 | 0.77 | NR4A2 (0.68) | NR4A2MAOBRAB9AMRGPRX4TSHR | |
| SCHEMBL3229701 | 0.76 | POLB (0.75) | NR4A2RAB9ANPC1TSHRSMN1; SMN2 | |
| SCHEMBL19984727 | 0.76 | NPC1 (0.67) | NR4A2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL1168262 | 0.75 | NR4A2 (1.00) | NR4A2MAOBMRGPRX4TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016278-A1 | FURAN-2-CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-02-07 | — | — | WO | claimed |
| WO-2008016278-A1 | FURAN-2-CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-02-07 | — | — | WO | disclosed |