Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.38 |
| ▸ | TK2 | O00142 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728681 | 0.99 | TK1 (0.39) | TK1LMNATSHRALBPKM | |
| SCHEMBL4727501 | 0.92 | TK1 (0.41) | TK1LMNATSHRALBPKM | |
| SCHEMBL29587983 | 0.91 | TK2 (0.44) | TK1TK2 | |
| SCHEMBL5163085 | 0.90 | TK2 (0.43) | TK1TK2 | |
| SCHEMBL1517629 | 0.86 | TK1 (0.44) | TK1LMNATSHRALBPKM | |
| SCHEMBL9113442 | 0.86 | TK1 (0.38) | TK1TK2 | |
| SCHEMBL27436150 | 0.85 | TK1 (0.43) | TK1LMNATSHRALBPKM | |
| SCHEMBL14388593 | 0.85 | TK1 (0.43) | TK1LMNATSHRALBPKM | |
| SCHEMBL887851 | 0.84 | TK1 (0.43) | TK1LMNATSHRALBPKM | |
| SCHEMBL29597386 | 0.84 | TK1 (0.39) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024826-A2 | RADIOHALOTHYMIDINES AND METHODS OF THEIR SYNTHESIS AND USE IN PET IMAGING OF CANCERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-02-28 | — | — | WO | disclosed |