SCHEMBL5163085

SCHEMBL5163085

CCCCC[C@]1(n2cc(C)c(=O)[nH]c2=O)C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK2 O00142 5/20 0.43
TK1 P04183 6/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29587983 0.99 TK2 (0.44) TK2TK1
SCHEMBL4728681 0.91 TK1 (0.39) TK1
SCHEMBL4725276 0.90 TK1 (0.38) TK2TK1
SCHEMBL887851 0.88 TK1 (0.43) TK1
SCHEMBL9113442 0.88 TK1 (0.38) TK2TK1
SCHEMBL4727501 0.87 TK1 (0.41) TK1
SCHEMBL14388593 0.87 TK1 (0.43) TK1
SCHEMBL27436150 0.87 TK1 (0.43) TK1
SCHEMBL28250600 0.86 TK1 (0.39) TK2TK1
SCHEMBL1517629 0.86 TK1 (0.44) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1032405-A4 ANTIMUTAGENIC COMPOSITIONS FOR TREATMENT AND PREVENTION OF PHOTODAMAGE TO SKIN WELLSTAT THERAPEUTICS CORP (US) 2007-05-02 EP claimed
US-20020006913-A1 ANTIMUTAGENIC COMPOSITIONS FOR TREATMENT AND PREVENTION OF PHOTODAMAGE TO SKIN PRO-NEURON, INC. 2002-01-17 US claimed
US-20010044421-A1 Administering to skin a composition containing deoxyribonucleosides in concentrations sufficient to enhance DNA repair or reduce mutation frequency in a vehicle capable of delivering deoxyribonucleosides to skin cells PRO-NEURON, INC. 2001-11-22 US claimed
US-20010044419-A1 Antimutagenic compositions for treatment and prevention of photodamage to skin PRO-NEURON, INC. 2001-11-22 US claimed
EP-1032405-A1 ANTIMUTAGENIC COMPOSITIONS FOR TREATMENT AND PREVENTION OF PHOTODAMAGE TO SKIN PRO-NEURON, INC. (US) 2000-09-06 EP claimed
WO-1999022741-A1 ANTIMUTAGENIC COMPOSITIONS FOR TREATMENT AND PREVENTION OF PHOTODAMAGE TO SKIN PRO-NEURON, INC. (US) 1999-05-14 WO claimed