SCHEMBL4725381

SCHEMBL4725381

CO[Si](OC)(OC)C(CCCN)C(C)N

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.32
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27757250 0.87 TRPV1 (0.30) TRPV1TRPA1
SCHEMBL603877 0.87 TRPV1 (0.30) TRPV1TRPA1
SCHEMBL28225272 0.81 CA12 (0.36)
SCHEMBL14359858 0.78 ALDH1A1 (0.36)
SCHEMBL27785484 0.77
SCHEMBL7146673 0.76 HTR2A (0.32)
SCHEMBL7772877 0.76
SCHEMBL28219576 0.75
SCHEMBL10704720 0.74
SCHEMBL6136548 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008021318-A2 COMPOSITE STRUCTURE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-02-21 WO disclosed
US-20080039576-A1 Vulcanizate composition GENERAL ELECTRIC COMPANY (US) 2008-02-14 US disclosed
US-20080038549-A1 Composite structure GENERAL ELECTRIC COMPANY (US) 2008-02-14 US disclosed