Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698390 | 0.93 | NFKB1 (0.32) | LMNA | |
| SCHEMBL9697294 | 0.91 | DNM1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL9698371 | 0.91 | DNM1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL9698909 | 0.91 | DNM1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL9698498 | 0.91 | DNM1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL9699800 | 0.91 | DNM1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL9698462 | 0.91 | DNM1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL9699811 | 0.91 | DNM1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL9699645 | 0.91 | DNM1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL539103 | 0.85 | GABRR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003072613-A1 | NITRO-DERIVATIVES OF EPOXYHEPARIN | NICOX S.A. (FR) | 2003-09-04 | — | — | WO | disclosed |
| EP-1340772-A1 | Nitro-derivatives of epoxyheparin | Nicox S.A. (FR) | 2003-09-03 | — | — | EP | disclosed |