Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838579 | 0.76 | KDM4E (0.51) | KDM4ELMNAMAPK1POLBNPY5R | |
| SCHEMBL3255854 | 0.74 | ALDH1A1 (0.48) | KDM4EALDH1A1HTTHPGD | |
| SCHEMBL29003631 | 0.72 | KDM4E (0.62) | KDM4ELMNAPOLBALDH1A1HTT | |
| SCHEMBL16487273 | 0.72 | NPSR1 (0.49) | KDM4ELMNAMAPK1POLBNPY5R | |
| SCHEMBL31294735 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL14208786 | 0.71 | ALDH1A1 (0.59) | KDM4ELMNAMAPK1POLBALDH1A1 | |
| SCHEMBL3511142 | 0.70 | KDM4E (0.56) | KDM4ELMNAMAPK1POLBNPY5R | |
| SCHEMBL30412874 | 0.70 | KDM4E (0.56) | KDM4ELMNAMAPK1POLBNPY5R | |
| SCHEMBL29139893 | 0.70 | ALDH1A1 (0.50) | KDM4ELMNAMAPK1POLBNPY5R | |
| SCHEMBL15466547 | 0.70 | ALDH1A1 (0.55) | KDM4ELMNAMAPK1POLBNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |