Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinamide SCHEMBL9208547 | 0.81 | KDM4E (0.78) | KDM4ELMNAMAPK1POLBALDH1A1 | |
| SCHEMBL5794326 | 0.80 | KDM4E (0.63) | KDM4ELMNAMAPK1POLBFDFT1 | |
| SCHEMBL6320906 | 0.80 | MAPT (0.67) | KDM4ELMNAMAPK1POLBFDFT1 | |
| SCHEMBL2600216 | 0.80 | KDM4E (0.62) | KDM4ELMNAMAPK1POLBFDFT1 | |
| SCHEMBL30150496 | 0.77 | KDM4E (0.68) | KDM4ELMNAMAPK1POLBALDH1A1 | |
| SCHEMBL7979578 | 0.77 | KDM4E (0.68) | KDM4ELMNAMAPK1POLBALDH1A1 | |
| SCHEMBL29733536 | 0.77 | KDM4E (0.59) | KDM4ELMNAMAPK1POLBFDFT1 | |
| SCHEMBL31694995 | 0.77 | KDM4E (0.60) | KDM4ELMNAMAPK1POLBFDFT1 | |
| SCHEMBL2852617 | 0.77 | KDM4E (0.67) | KDM4ELMNAMAPK1POLBALDH1A1 | |
| SCHEMBL4849333 | 0.77 | KDM4E (0.67) | KDM4ELMNAMAPK1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |