SCHEMBL6320906

SCHEMBL6320906

CCn1c2ccccc2c2cc(CCN)ccc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.67
KDM4E B2RXH2 4/20 0.67
KMT2A Q03164 3/20 0.67
MAPK1 P28482 2/20 0.67
MEN1 O00255 2/20 0.67
ALDH1A1 P00352 2/20 0.67
HTT P42858 2/20 0.67
HPGD P15428 1/20 0.67
HBB P68871 1/20 0.67
HSD17B10 Q99714 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
LMNA P02545 3/20 0.63
POLB P06746 2/20 0.63
TP53 P04637 8/20 0.56
SMN1; SMN2 Q16637 1/20 0.54
FDFT1 P37268 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.51
THRB P10828 1/20 0.51
PKM P14618 1/20 0.50
MCHR2 Q969V1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2852617 0.87 KDM4E (0.67) MAPTKDM4EKMT2AMAPK1MEN1
SCHEMBL2600216 0.87 KDM4E (0.62) MAPTKDM4EKMT2AMAPK1MEN1
SCHEMBL29733536 0.84 KDM4E (0.59) MAPTKDM4EKMT2AMAPK1MEN1
SCHEMBL5794326 0.84 KDM4E (0.63) MAPTKDM4EKMT2AMAPK1MEN1
SCHEMBL12158838 0.83 KDM4E (0.66) MAPTKDM4EKMT2AMAPK1MEN1
SCHEMBL10163400 0.83 KDM4E (0.66) MAPTKDM4EKMT2AMAPK1MEN1
SCHEMBL27275930 0.82 MAPT (0.68) MAPTKDM4EKMT2AMAPK1MEN1
SCHEMBL22023745 0.82 FDFT1 (0.58) MAPTKDM4EKMT2AMAPK1MEN1
SCHEMBL29643256 0.81 KDM4E (0.62) MAPTKDM4EKMT2AMAPK1MEN1
SCHEMBL4849333 0.81 KDM4E (0.67) MAPTKDM4EKMT2AMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1755369-B Reagent and kit for staining quantitative detection of semen leucocyte subpopulations, and detection method thereof SHENZHEN HUAKANG BIOMEDICAL ENGINEERING CO LTD 2010-06-30 CN disclosed
CN-1755369-A Reagent and kit for staining quantitative detection of semen leucocyte subpopulations, and detection method thereof SHENZHEN HUAKANG BIOMEDICAL EN (CN) 2006-04-05 CN disclosed
US-20050032129-A1 Detection of antigen by immunohistochemical staining KAGOSHIMA UNIVERSITY (JP) 2005-02-10 US disclosed