Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.49 |
| ▸ | ADK | P55263 | 3/20 | 0.38 |
| ▸ | ATR | Q13535 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761910 | 0.82 | NOS1 (0.56) | NOS1ADKATRPIK3CAMTOR | |
| Cyclopropane Carboxylic Acid SCHEMBL4725700 | 0.80 | NOS1 (0.52) | NOS1ADKATRPIK3CAMTOR | |
| SCHEMBL4450316 | 0.74 | NOS1 (0.82) | NOS1ADKPIK3CAMTORPIK3CG | |
| SCHEMBL4458075 | 0.71 | NOS1 (0.64) | NOS1ADKATRPIK3CAMTOR | |
| SCHEMBL3770114 | 0.71 | NOS1 (0.64) | NOS1ADKATR | |
| SCHEMBL3770209 | 0.70 | NOS1 (0.71) | NOS1ATRPIK3CAMTORPIK3CG | |
| SCHEMBL3752640 | 0.70 | NOS1 (0.64) | NOS1ADKATRHDAC6PIK3CA | |
| SCHEMBL3769685 | 0.70 | NOS1 (0.73) | NOS1ADKATRPIK3CAMTOR | |
| SCHEMBL3765210 | 0.70 | NOS1 (0.67) | NOS1ADKPIK3CAMTOR | |
| SCHEMBL3766169 | 0.70 | NOS1 (0.64) | NOS1ADKATRPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009079-A2 | SUBSTITUTED PTERIDINES USEFUL FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | disclosed |