Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.59 |
| ▸ | PDE2A | O00408 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.54 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.54 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.54 |
| ▸ | GAPDH | P04406 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725716 | 1.00 | LMNA (0.60) | LMNANT5EHIF1AADORA3ADORA2A | |
| SCHEMBL6663083 | 0.93 | LMNA (0.62) | LMNANT5EHIF1AADORA3ADORA2A | |
| SCHEMBL4388119 | 0.87 | P2RY1 (0.60) | SMN1; SMN2 | |
| SCHEMBL4388097 | 0.87 | P2RY1 (0.60) | SMN1; SMN2 | |
| SCHEMBL5698874 | 0.86 | LMNA (0.55) | LMNANT5EHIF1AADORA3ADORA2A | |
| SCHEMBL7030265 | 0.86 | LMNA (0.55) | LMNANT5EHIF1AADORA3ADORA2A | |
| SCHEMBL2424283 | 0.85 | LMNA (0.64) | LMNANT5EHIF1AADORA3ADORA2A | |
| SCHEMBL4374446 | 0.84 | ADORA2A (0.63) | LMNANT5EHIF1AADORA3ADORA2A | |
| SCHEMBL21385677 | 0.84 | ADORA2A (0.63) | LMNANT5EHIF1AADORA3ADORA2A | |
| SCHEMBL899617 | 0.84 | LMNA (0.62) | LMNANT5EHIF1AADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022469-A1 | 2'-DEOXY-2'-FLUORO-β-D-ARABINONUCLEOSIDE 5'-TRIPHOSPHATES AND THEIR USE IN ENZYMATIC NUCLEIC ACID SYNTHESIS | MCGILL UNIVERSITY (CA) | 2008-02-28 | — | — | WO | disclosed |