Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276677 | 1.00 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| Acetone SCHEMBL472485 | 0.96 | ADORA1 (0.45) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| SCHEMBL13384997 | 0.86 | ADORA1 (0.67) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| Acetone SCHEMBL472483 | 0.77 | AHCY (0.38) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| Acetone SCHEMBL472736 | 0.76 | ADORA1 (0.62) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| Acetone SCHEMBL472703 | 0.75 | ADORA1 (0.52) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| SCHEMBL472527 | 0.74 | ADORA1 (0.67) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| SCHEMBL6397659 | 0.74 | ADORA1 (0.74) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| SCHEMBL13384992 | 0.73 | ADORA1 (0.51) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| SCHEMBL6901588 | 0.67 | DOT1L (0.67) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2412716-A1 | Partial and full agonists of A1 adenosine receptors | CV THERAPEUTICS, INC. (US) | 2012-02-01 | — | — | EP | disclosed |