Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 13/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726344 | 1.00 | ALDH1A1 (0.35) | ALDH1A1CHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL1109817 | 0.99 | CHRM3 (0.36) | ALDH1A1CHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL14290902 | 0.89 | ALDH1A1 (0.37) | ALDH1A1CHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL1109808 | 0.88 | CHRM3 (0.38) | ALDH1A1CHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL13093510 | 0.87 | CHRM3 (0.39) | ALDH1A1CHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL4726275 | 0.85 | CHRM2 (0.34) | CHRM3CHRM2CHRM4CHRM1CHRM5 | |
| SCHEMBL12855710 | 0.85 | CHRM3 (0.36) | ALDH1A1CHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL12855714 | 0.85 | CHRM3 (0.41) | ALDH1A1CHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL4778829 | 0.84 | CHRM3 (0.34) | ALDH1A1CHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL1109850 | 0.83 | CHRM3 (0.40) | ALDH1A1CHRM3CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017827-A2 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-14 | — | — | WO | disclosed |