Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 10/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12855714 | 0.87 | CHRM3 (0.41) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 | |
| SCHEMBL14290902 | 0.87 | ALDH1A1 (0.37) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 | |
| SCHEMBL1109808 | 0.86 | CHRM3 (0.38) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 | |
| SCHEMBL13093510 | 0.85 | CHRM3 (0.39) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 | |
| SCHEMBL12855710 | 0.84 | CHRM3 (0.36) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 | |
| SCHEMBL4726344 | 0.84 | ALDH1A1 (0.35) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 | |
| SCHEMBL4725876 | 0.84 | ALDH1A1 (0.35) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 | |
| SCHEMBL1109851 | 0.83 | CHRM3 (0.40) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 | |
| SCHEMBL1109850 | 0.83 | CHRM3 (0.40) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 | |
| SCHEMBL1110599 | 0.83 | CHRM3 (0.40) | CHRM3CHRM2CHRM4CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017827-A2 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008017827-A2 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-14 | — | — | WO | disclosed |