Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 3/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | THPO | P40225 | 1/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.98 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.98 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.98 |
| ▸ | MEN1 | O00255 | 2/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.98 |
| ▸ | GAA | P10253 | 1/20 | 0.98 |
| ▸ | HTT | P42858 | 1/20 | 0.98 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.98 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.98 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.98 |
| ▸ | TP53 | P04637 | 1/20 | 0.98 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.98 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12119008 | 1.00 | TSHR (1.00) | TSHRADORA2APMP22SMN1; SMN2TDP1 | |
| SCHEMBL145856 | 1.00 | TSHR (1.00) | TSHRADORA2APMP22SMN1; SMN2TDP1 | |
| SCHEMBL472771 | 1.00 | TSHR (1.00) | TSHRADORA2APMP22SMN1; SMN2TDP1 | |
| SCHEMBL27097764 | 1.00 | TSHR (1.00) | TSHRADORA2APMP22SMN1; SMN2TDP1 | |
| SCHEMBL17033118 | 1.00 | TSHR (1.00) | TSHRADORA2APMP22SMN1; SMN2TDP1 | |
| SCHEMBL145857 | 1.00 | TSHR (1.00) | TSHRADORA2APMP22SMN1; SMN2TDP1 | |
| SCHEMBL472589 | 1.00 | TSHR (1.00) | TSHRADORA2APMP22SMN1; SMN2TDP1 | |
| SCHEMBL16081270 | 1.00 | TSHR (1.00) | TSHRADORA2APMP22SMN1; SMN2TDP1 | |
| N6-Cyclopentyladenosine SCHEMBL18908968 | 0.99 | ADORA3 (1.00) | TSHRADORA2APMP22SMN1; SMN2TDP1 | |
| N6-Cyclopentyladenosine SCHEMBL120481 | 0.99 | ADORA3 (1.00) | TSHRADORA2APMP22SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2412716-A1 | Partial and full agonists of A1 adenosine receptors | CV THERAPEUTICS, INC. (US) | 2012-02-01 | — | — | EP | disclosed |