Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.39 |
| ▸ | HTR2C | P28335 | 12/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4796153 | 0.84 | MAPT (0.43) | HTR2AHTR2CMAOB | |
| SCHEMBL4780197 | 0.80 | HTR2A (0.42) | HTR2AHTR2C | |
| SCHEMBL4780191 | 0.79 | HTR2A (0.62) | HTR2AHTR2C | |
| SCHEMBL4727771 | 0.79 | HTR2A (0.57) | HTR2AHTR2C | |
| SCHEMBL4727184 | 0.79 | HTR2A (0.60) | HTR2AHTR2C | |
| SCHEMBL4725894 | 0.76 | HTR2A (0.59) | HTR2AHTR2CTSHR | |
| Hydrochloric Acid SCHEMBL6983043 | 0.74 | ALDH1A1 (0.43) | MAOBAKR1B1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6981973 | 0.72 | GAA (0.44) | MAOBAKR1B1MEN1TSHRKMT2A | |
| SCHEMBL1530265 | 0.71 | HTR2A (0.45) | HTR2AHTR2C | |
| SCHEMBL4778434 | 0.71 | HTR2A (0.37) | HTR2AHTR2CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008027483-A1 | BENZOFURAN DERIVATIVES AS MODULATORS OF THE 5-HT2A RECEPTOR | ARENA PHARMACEUTICALS, INC. (US) | 2008-03-06 | — | — | WO | disclosed |