Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4727423 | 0.99 | LMNA (0.42) | LMNATDP1MEN1MAPTTHRB | |
| SCHEMBL7750100 | 0.88 | LMNA (0.47) | LMNATDP1MEN1MAPTTHRB | |
| Bromide SCHEMBL6537215 | 0.87 | MEN1 (0.41) | LMNATDP1MEN1MAPTTHRB | |
| SCHEMBL634270 | 0.86 | MAPT (0.42) | LMNATDP1MEN1MAPTTHRB | |
| SCHEMBL135011 | 0.85 | LMNA (0.41) | LMNATDP1MEN1MAPTTHRB | |
| Potassium Ion SCHEMBL7745644 | 0.85 | MAPT (0.41) | LMNATDP1MEN1MAPTTHRB | |
| SCHEMBL31166034 | 0.85 | MAPT (0.41) | LMNATDP1MEN1MAPTTHRB | |
| Potassium Ion SCHEMBL30656252 | 0.85 | MAPT (0.41) | LMNATDP1MEN1MAPTTHRB | |
| SCHEMBL29949152 | 0.84 | LMNA (0.44) | LMNATDP1MEN1MAPTTHRB | |
| SCHEMBL559842 | 0.84 | LMNA (0.40) | LMNATDP1MEN1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008027075-A2 | SULFHYDRYL-REACTIVE, WATER SOLUBLE DYES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-03-06 | — | — | WO | disclosed |