Sugi Predict

Sugi Predict / Compounds / SCHEMBL135011

SCHEMBL135011

SCHEMBL135011

CC1=[N+](CCCS(=O)(=O)O)c2ccc(S(=O)(=O)[O-])cc2C1(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ RECQL P46063 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ PTPN1 P18031 1/20 0.35
▸ MLNR O43193 1/20 0.30
▸ NR1I2 O75469 1/20 0.30
▸ PGR P06401 1/20 0.30
▸ ADRB1 P08588 1/20 0.30
▸ ADORA3 P0DMS8 1/20 0.30
▸ CHRM1 P11229 1/20 0.30
▸ DRD2 P14416 1/20 0.30
▸ ADRA2B P18089 1/20 0.30
▸ ADRA2C P18825 1/20 0.30
▸ CHRM3 P20309 1/20 0.30
▸ CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL559842 0.96 LMNA (0.40) LMNATDP1MEN1MAPTTHRB
SCHEMBL1656985 0.91 MEN1 (0.42) LMNATDP1MEN1MAPTTHRB
SCHEMBL5271477 0.90 MEN1 (0.41) LMNATDP1MEN1MAPTTHRB
SCHEMBL5271474 0.90 MEN1 (0.41) LMNATDP1MEN1MAPTTHRB
SCHEMBL721215 0.90 MEN1 (0.41) LMNATDP1MEN1MAPTTHRB
SCHEMBL634270 0.89 MAPT (0.42) LMNATDP1MEN1MAPTTHRB
SCHEMBL3859355 0.88 MEN1 (0.41) LMNATDP1MEN1MAPTTHRB
SCHEMBL137086 0.87 LMNA (0.31) LMNATDP1PTPN1
SCHEMBL3242102 0.87 LMNA (0.31) LMNATDP1PTPN1
SCHEMBL3242091 0.86 LMNA (0.30) LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240132948-A1 Cyanine Dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2024-04-25 — — US disclosed
US-11624089-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-04-11 — — US disclosed
US-20200232023-A1 CYANINE DYES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2020-07-23 — — US disclosed
US-10392659-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2019-08-27 — — US disclosed
US-9920365-B2 Functionalized cyanine dyes (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2018-03-20 — — US disclosed
US-9738786-B2 Dyes for labelling molecular ligands ILLUMINA CAMBRIDGE LIMITED (GB) 2017-08-22 — — US disclosed
US-20170183501-A1 Cyanine Dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2017-06-29 — — US disclosed
EP-2758475-B1 DYES FOR LABELLING MOLECULAR LIGANDS ILLUMINA CAMBRIDGE LTD (GB) 2017-04-26 — — EP disclosed
US-20160355683-A1 DYES FOR LABELLING MOLECULAR LIGANDS ILLUMINA CAMBRIDGE LIMITED (GB) 2016-12-08 — — US disclosed
US-9441270-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-09-13 — — US disclosed
US-20120058469-A1 FUNCTIONALIZED CYANINE DYES (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-08 — — US disclosed
US-20120058482-A1 FUNCTIONALIZED CYANINE DYES (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-08 — — US disclosed
US-20120052506-A1 CYANINE DYES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-01 — — US disclosed
WO-2012027618-A2 FUNCTIONALIZED CYANINE DYES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-01 — — WO disclosed
WO-2012027623-A2 CYANINE DYES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-01 — — WO disclosed
US-7411068-B2 Luminescent compounds SETA BIOMEDICALS, LLC 2008-08-12 — — US disclosed
US-20070281363-A1 Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence Terpetschnig, Ewald (US) 2007-12-06 — — US disclosed
US-20050202565-A1 Luminescent compounds SETA BIOMEDICALS, LLC 2005-09-15 — — US disclosed
EP-0979104-B1 SONODYNAMIC THERAPY USING AN ULTRASOUND SENSITIZER COMPOUND AMERSHAM HEALTH AS (NO) 2004-09-15 — — EP disclosed
US-6498945-B1 FREE RADICAL GENERATION OF WATER SOLUBLE POLYMER TO ENHANCE CYTOPATHOGENIC EFFICACY AMERSHAM HEALTH AS (NO) 2002-12-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132948-A1 Cyanine Dyes ABCG2, IK, ACR LMNA 1823/4885TDP1 2918/4885MEN1 2288/4885
US-10392659-B2 Cyanine dyes ABCG2, IK, ACR LMNA 1823/4885TDP1 2918/4885MEN1 2288/4885
US-11624089-B2 Cyanine dyes ABCG2, IK, ACR LMNA 1823/4885TDP1 2918/4885MEN1 2288/4885
US-20120052506-A1 CYANINE DYES ABCG2, IK, ACR LMNA 1823/4885TDP1 2918/4885MEN1 2288/4885
US-20200232023-A1 CYANINE DYES ABCG2, IK, ACR LMNA 1823/4885TDP1 2918/4885MEN1 2288/4885
US-20120058482-A1 FUNCTIONALIZED CYANINE DYES (PEG) ACR, IK, EGFR LMNA 2335/4885TDP1 3995/4885MEN1 3947/4885
US-20070281363-A1 Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence SPR, SRRT, SQLE LMNA 1873/4885TDP1 4192/4885MEN1 2672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.