Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.43 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.42 |
| ▸ | FRK | P42685 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726017 | 0.90 | CCNT1 (0.41) | MAPK14EGLN1RAF1BRAF | |
| SCHEMBL4728338 | 0.89 | RAF1 (0.39) | MAPK14EPHA3FRKRAF1BRAF | |
| SCHEMBL4730519 | 0.87 | ABCG2 (0.45) | — | |
| SCHEMBL4782731 | 0.86 | RAF1 (0.39) | MAPK14RAF1BRAF | |
| SCHEMBL4725975 | 0.86 | MAPK14 (0.41) | MAPK14EGLN1RAF1BRAF | |
| SCHEMBL4730324 | 0.85 | MAPK14 (0.42) | MAPK14RAF1BRAF | |
| SCHEMBL4728030 | 0.85 | MAPK14 (0.42) | MAPK14RAF1BRAF | |
| SCHEMBL4725924 | 0.85 | MAPK14 (0.43) | MAPK14RAF1BRAF | |
| SCHEMBL4725981 | 0.84 | MAPK14 (0.42) | MAPK14RAF1BRAF | |
| SCHEMBL4726042 | 0.84 | MAPK14 (0.42) | MAPK14EGLN1RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |