Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.56 |
| ▸ | SPR | P35270 | 2/20 | 0.46 |
| ▸ | QDPR | P09417 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 4/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | USP5 | P45974 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782539 | 0.88 | IDO1 (0.47) | IDO1SPRQDPRCCR1MAPT | |
| SCHEMBL3418716 | 0.86 | USP5 (0.50) | IDO1QDPRCCR1USP5HDAC6 | |
| SCHEMBL17398136 | 0.84 | QDPR (0.56) | IDO1SPRQDPRMAPTHSD11B1 | |
| SCHEMBL3817499 | 0.82 | QDPR (0.44) | IDO1QDPRCCR1USP5HDAC6 | |
| SCHEMBL2098866 | 0.81 | HSD11B1 (0.58) | IDO1CCR1MAPTKCNH2HSD11B1 | |
| SCHEMBL25430208 | 0.81 | QDPR (0.56) | IDO1SPRQDPRCCR1USP5 | |
| SCHEMBL4846419 | 0.80 | MAPT (0.51) | IDO1MAPT | |
| SCHEMBL28096680 | 0.79 | HDAC1 (0.46) | IDO1QDPRUSP5HDAC6 | |
| SCHEMBL27650942 | 0.79 | QDPR (0.59) | QDPR | |
| SCHEMBL5024448 | 0.79 | NPC1 (0.51) | IDO1MGLLCYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008012622-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR | PFIZER PRODUCTS INC. (US) | 2008-01-31 | — | — | WO | disclosed |