Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379305 | 1.00 | MAPT (0.53) | MAPTDGKALMNAKDM4EDUSP3 | |
| SCHEMBL9723687 | 1.00 | MAPT (0.53) | MAPTDGKALMNAKDM4EDUSP3 | |
| SCHEMBL28605449 | 1.00 | MAPT (0.53) | MAPTDGKALMNAKDM4EDUSP3 | |
| SCHEMBL28358120 | 1.00 | MAPT (0.53) | MAPTDGKALMNAKDM4EDUSP3 | |
| SCHEMBL28005808 | 1.00 | MAPT (0.53) | MAPTDGKALMNAKDM4EDUSP3 | |
| SCHEMBL20853447 | 1.00 | MAPT (0.53) | MAPTDGKALMNAKDM4EDUSP3 | |
| SCHEMBL28285143 | 0.98 | MAPT (0.51) | MAPTDGKALMNAKDM4EDUSP3 | |
| SCHEMBL27796633 | 0.91 | DGKA (0.57) | MAPTDGKALMNADUSP3 | |
| SCHEMBL9723690 | 0.88 | PAM (0.54) | MAPTDGKALMNAKDM4EDUSP3 | |
| SCHEMBL9220943 | 0.88 | PAM (0.54) | MAPTDGKALMNAKDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008027063-A1 | ANTI-AGING SKIN PREPARATION | BLASS JOHN P (US) | 2008-03-06 | — | — | WO | claimed |
| US-20080057088-A1 | Anti-aging cream | BLASS JOHN P | 2008-03-06 | — | — | US | claimed |
| US-8435547-B2 | Krebs cycle intermediate or precursor of Krebs cycle intermediate, pharmaceutically acceptable topical vehicle comprising a mitochondrial fuel or substance that is efficiently convertible to mitochondrial fuel by normal skin cell metabolism; for stimulating mitochondrial activity in skin cells | Blass, John P. (US) | 2013-05-07 | — | — | US | disclosed |
| WO-2008027063-A1 | ANTI-AGING SKIN PREPARATION | BLASS JOHN P (US) | 2008-03-06 | — | — | WO | disclosed |
| US-20080057088-A1 | Anti-aging cream | BLASS JOHN P | 2008-03-06 | — | — | US | disclosed |