Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | BHMT | Q93088 | 1/20 | 0.42 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14862449 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL25660992 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL6078029 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL1234861 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL1234860 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL8015345 | 0.81 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL20012329 | 0.81 | SLC7A5 (0.77) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL2295882 | 0.81 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL8634662 | 0.81 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL9282867 | 0.81 | SLC7A5 (0.77) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013262-A1 | L-LEUCINE HYDROXYLASE AND DNA ENCODING THE ENZYME | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-01-31 | — | — | WO | disclosed |