Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | BHMT | Q93088 | 1/20 | 0.42 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14862449 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL25660992 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL1234861 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL1234860 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL4726047 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL8015345 | 0.81 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL20012329 | 0.81 | SLC7A5 (0.77) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL2295882 | 0.81 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL8634662 | 0.81 | SLC7A5 (0.62) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 | |
| SCHEMBL9282867 | 0.81 | SLC7A5 (0.77) | SLC7A5SLC1A1SLC1A2SLC1A3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144899-B2 | Thrombin inhibitors | MERCK & CO., INC. (US) | 2006-12-05 | — | — | US | disclosed |
| US-20040073025-A1 | Thrombin inhibitors | MERCK SHARP & DOHME CORP. | 2004-04-15 | — | — | US | disclosed |
| WO-2002064559-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040073025-A1 | Thrombin inhibitors | F2, F11, F10 | SLC7A5 4181/4885SLC1A1 4642/4885SLC1A2 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.