Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583157 | 0.89 | MALT1 (0.51) | MALT1ALDH1A1 | |
| SCHEMBL4583236 | 0.87 | ALDH1A1 (0.54) | MALT1ALDH1A1POLB | |
| SCHEMBL4582726 | 0.87 | POLB (0.53) | MALT1ALDH1A1POLB | |
| SCHEMBL4584076 | 0.81 | PKM (0.54) | MALT1ALDH1A1POLB | |
| SCHEMBL4583601 | 0.80 | KMT2A (0.52) | MALT1ALDH1A1 | |
| SCHEMBL4725033 | 0.80 | MALT1 (0.47) | MALT1 | |
| SCHEMBL4725551 | 0.79 | EGFR (0.43) | ALDH1A1 | |
| SCHEMBL4582850 | 0.79 | ALDH1A1 (0.53) | MALT1ALDH1A1CCNE1CDK2 | |
| SCHEMBL4582822 | 0.79 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL4583335 | 0.78 | MEN1 (0.55) | MALT1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028690-A1 | 1-(HET)ARYL-3-[HETARYL-PIPERIDIN-4-YL]-THIOUREAS AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |