Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.71 |
| ▸ | NPC1 | O15118 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24335459 | 0.82 | RAB9A (0.67) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL4713116 | 0.81 | NPC1 (0.76) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL15066680 | 0.79 | RAB9A (0.71) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL30708168 | 0.78 | SUV39H2 (0.48) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL15069225 | 0.78 | SUV39H2 (0.48) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL16669697 | 0.78 | RAB9A (0.44) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL15068750 | 0.77 | RAB9A (0.43) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL15068705 | 0.77 | RAB9A (0.73) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL15068854 | 0.76 | RAB9A (0.43) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL15069258 | 0.75 | RAB9A (0.41) | RAB9ANPC1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029152-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |