Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1459437 | 0.81 | CA1 (0.71) | KDM4ERAB9ACA1CA2HSD17B10 | |
| SCHEMBL30184445 | 0.81 | CA1 (0.71) | KDM4ERAB9ACA1CA2HSD17B10 | |
| SCHEMBL19271274 | 0.80 | HSD17B10 (0.64) | KDM4ERAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL14157802 | 0.79 | CA1 (0.71) | KDM4ERAB9ACA1CA2HSD17B10 | |
| SCHEMBL13877234 | 0.79 | PTGDR2 (0.46) | KDM4ERAB9APTGDR2MEN1KMT2A | |
| SCHEMBL3362461 | 0.78 | TSPO (0.55) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL15899412 | 0.78 | HTR6 (0.57) | KDM4ERAB9ACA1CA2HSD17B10 | |
| SCHEMBL13877230 | 0.78 | BCHE (0.55) | KDM4ERAB9APTGDR2HSD17B10RORC | |
| SCHEMBL4727325 | 0.78 | MAPT (0.59) | KDM4ERAB9ACA1CA2HSD17B10 | |
| SCHEMBL19271276 | 0.78 | KDM4E (0.52) | KDM4ERAB9ACA1CA2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |