SCHEMBL4726530

SCHEMBL4726530

CCCC(=NOCCn1c2ccccc2c2ccccc21)c1ccc(OC(CC)C(=O)O)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 6/20 0.44
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
PPARA Q07869 9/20 0.40
PPARG P37231 8/20 0.40
PPARD Q03181 1/20 0.40
CNR2 P34972 1/20 0.38
PTGER4 P35408 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4726529 1.00 PLA2G2A (0.44) PLA2G2AALDH1A1HPGDPPARAPPARG
SCHEMBL4727910 0.91 PPARA (0.41) PLA2G2AALDH1A1HPGDPPARAPPARG
SCHEMBL4727908 0.91 PPARA (0.41) PLA2G2AALDH1A1HPGDPPARAPPARG
SCHEMBL4726775 0.89 PLA2G2A (0.43) PLA2G2AALDH1A1HPGDPPARAPPARG
SCHEMBL4729118 0.87 PPARA (0.44) PLA2G2AALDH1A1HPGDPPARAPPARG
SCHEMBL4725557 0.86 TSHR (0.39) PLA2G2AALDH1A1PPARAPPARGPPARD
SCHEMBL4725558 0.86 TSHR (0.39) PLA2G2AALDH1A1PPARAPPARGPPARD
SCHEMBL4727953 0.84 PLA2G2A (0.49) PLA2G2AALDH1A1HPGDPPARAPPARG
SCHEMBL4726512 0.84 PLA2G2A (0.49) PLA2G2AALDH1A1HPGDPPARAPPARG
SCHEMBL4727902 0.79 PPARA (0.42) PLA2G2AHPGDPPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed