Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.42 |
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726776 | 0.90 | PPARA (0.44) | PPARAPPARGPPARDPLA2G2AHPGD | |
| SCHEMBL4729371 | 0.86 | PPARA (0.35) | PPARAPPARGPPARDPTGDR2 | |
| SCHEMBL4726516 | 0.84 | PSEN1 (0.44) | PPARAPPARGPPARDPLA2G2AHPGD | |
| SCHEMBL4729118 | 0.84 | PPARA (0.44) | PPARAPPARGPPARDPLA2G2AHPGD | |
| SCHEMBL4726775 | 0.81 | PLA2G2A (0.43) | PPARAPPARGPPARDPLA2G2AHPGD | |
| SCHEMBL4727910 | 0.80 | PPARA (0.41) | PPARAPPARGPPARDPLA2G2AHPGD | |
| SCHEMBL4727908 | 0.80 | PPARA (0.41) | PPARAPPARGPPARDPLA2G2AHPGD | |
| SCHEMBL4726530 | 0.79 | PLA2G2A (0.44) | PPARAPPARGPPARDPLA2G2AHPGD | |
| SCHEMBL4726529 | 0.79 | PLA2G2A (0.44) | PPARAPPARGPPARDPLA2G2AHPGD | |
| SCHEMBL4728218 | 0.78 | PPARA (0.47) | PPARAPPARGPPARDPTGDR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |