Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.72 |
| ▸ | PGR | P06401 | 6/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.72 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.72 |
| ▸ | AR | P10275 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | TNF | P01375 | 1/20 | 0.72 |
| ▸ | IL6 | P05231 | 1/20 | 0.72 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.72 |
| ▸ | GLUL | P15104 | 1/20 | 0.72 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.72 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647326 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL3775851 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL12313064 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL23832187 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL647327 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL25129199 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL24861840 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL24622464 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL21293123 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL1753572 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015696-A2 | PROCESS FOR PREPARING CICLESONIDE | CADILA HEALTHCARE LIMITED (IN) | 2008-02-07 | — | — | WO | disclosed |