Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.72 |
| ▸ | PGR | P06401 | 6/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.72 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.72 |
| ▸ | AR | P10275 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | TNF | P01375 | 1/20 | 0.72 |
| ▸ | IL6 | P05231 | 1/20 | 0.72 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.72 |
| ▸ | GLUL | P15104 | 1/20 | 0.72 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.72 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647326 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL3775851 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL4726540 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL12313064 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL23832187 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL25129199 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL24861840 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL24622464 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL21293123 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL1753572 | 1.00 | NR3C1 (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118085006-A | Method for large-scale preparation of budesonide | 杭州新曦科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| EP-3250211-B1 | NOVEL PROCESS FOR PREPARATION OF GLUCOCORTICOID STEROIDS | CORAL DRUGS PVT LTD (IN) | 2021-12-22 | — | — | EP | claimed |
| EP-2108653-B2 | Process for preparing budesonide | IND CHIMICA SRL (IT) | 2016-08-31 | — | — | EP | claimed |
| EP-2108653-B1 | Process for preparing budesonide | IND CHIMICA SRL (IT) | 2013-08-07 | — | — | EP | claimed |
| EP-2262823-B1 | PROCESS FOR THE PREPARATION OF PREGNANE DERIVATIVES | FARMABIOS SPA (IT) | 2013-01-23 | — | — | EP | claimed |
| US-8119793-B2 | Process for preparing budesonide | INDUSTRIALE CHIMICA S.R.L. (IT) | 2012-02-21 | — | — | US | claimed |
| US-20100331539-A1 | PROCESS FOR THE PREPARATION OF PREGNANE DERIVATIVES | FARMABIOS S.P.A. (IT) | 2010-12-30 | — | — | US | claimed |
| EP-2265628-A1 | PURIFICATION OF AIR SENSITIVE STEROIDS | Sicor, Inc. (US) | 2010-12-29 | — | — | EP | claimed |
| EP-2262823-A2 | PROCESS FOR THE PREPARATION OF PREGNANE DERIVATIVES | Farmabios S.p.A. (IT) | 2010-12-22 | — | — | EP | claimed |
| US-20090259037-A1 | PROCESS FOR PREPARING BUDESONIDE | INDUSTRIALE CHIMICA S.R.L. (IT) | 2009-10-15 | — | — | US | claimed |
| EP-2108653-A1 | Process for preparing budesonide | INDUSTRIALE CHIMICA S.r.l. (IT) | 2009-10-14 | — | — | EP | claimed |
| WO-2009117120-A1 | PURIFICATION OF AIR SENSITIVE STEROIDS | SICOR INC. (US) | 2009-09-24 | — | — | WO | claimed |
| US-20090240049-A1 | Purification of air sensitive steroids | SICOR INC. | 2009-09-24 | — | — | US | claimed |
| WO-2009112557-A2 | PROCESS FOR THE PREPARATION OF PREGNANE DERIVATIVES | FARMABIOS S.P.A. (IT) | 2009-09-17 | — | — | WO | claimed |
| WO-2005044759-A2 | ACETALIZATION PROCESS FOR PREPARATION OF STEROID COMPOUNDS | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2005-05-19 | — | — | WO | claimed |
| US-5733901-A | ADMINISTERING TO TREAT SKIN AND RESPIRATORY SYSTEM DISORDERS, INFLAMMATORY DISORDERS OF THE BOWEL, AND ALLERGIC RHINITIS/CONJUNCTIVITIS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-03-31 | — | — | US | claimed |
| EP-0701565-A1 | NEW PREDNISOLONE DERIVATES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1996-03-20 | — | — | EP | claimed |
| WO-1994022899-A1 | NEW PREDNISOLONE DERIVATES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1994-10-13 | — | — | WO | claimed |
| US-20240307415-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | JIANGSU SIMCERE PHARMACEUTICAL CO., LTD. (CN) | 2024-09-19 | — | — | US | disclosed |
| US-4820700-A | ANTIINFLAMMATORY AGENTS | AKTIEBOLAGET DRACO (SE) | 1989-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240049-A1 | Purification of air sensitive steroids | CYP17A1, CYP11B1, CYP11B2 | NR3C1 31/4885HIF1A 493/4885PGR 2988/4885 |
| US-20090259037-A1 | PROCESS FOR PREPARING BUDESONIDE | CYP11B2, CYP11B1, HSD11B2 | NR3C1 38/4885HIF1A 744/4885PGR 2246/4885 |
| US-20100331539-A1 | PROCESS FOR THE PREPARATION OF PREGNANE DERIVATIVES | CYP17A1, CYP21A2, CYP11B1 | NR3C1 19/4885HIF1A 2713/4885PGR 95/4885 |
| US-20240307415-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | NR5A1, HSD17B7, CYP17A1 | NR3C1 19/4885HIF1A 2718/4885PGR 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.