Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780102 | 0.92 | ROCK1 (0.40) | ENPP2ROCK1ROCK2MAPK1TSHR | |
| SCHEMBL4957984 | 0.89 | ENPP2 (0.46) | ENPP2ROCK1ROCK2MAPK1TSHR | |
| Hydrochloric Acid SCHEMBL4845630 | 0.88 | ENPP2 (0.46) | ENPP2ROCK1ROCK2MAPK1TSHR | |
| SCHEMBL4728299 | 0.86 | ROCK1 (0.44) | ENPP2ROCK1ROCK2MAPK1TSHR | |
| SCHEMBL4776692 | 0.85 | ENPP2 (0.44) | ENPP2ROCK1ROCK2MAPK1TSHR | |
| SCHEMBL4725275 | 0.82 | TSHR (0.40) | ENPP2ROCK1ROCK2MAPK1TSHR | |
| SCHEMBL4725225 | 0.80 | SLC2A1 (0.43) | ROCK1ROCK2MAPK1TSHRKDM4E | |
| SCHEMBL4779148 | 0.80 | MEN1 (0.45) | ENPP2ROCK1ROCK2MAPK1GCK | |
| SCHEMBL352216 | 0.80 | ROCK1 (0.43) | ENPP2ROCK1ROCK2MAPK1TSHR | |
| Hydrochloric Acid SCHEMBL4726458 | 0.80 | SLC2A1 (0.43) | ROCK1ROCK2MAPK1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011191-A1 | ANTIBACTERIAL HETEROCYCLIC UREAS | REPLIDYNE, INC. (US) | 2008-01-24 | — | — | WO | claimed |
| WO-2008011191-A1 | ANTIBACTERIAL HETEROCYCLIC UREAS | REPLIDYNE, INC. (US) | 2008-01-24 | — | — | WO | disclosed |