Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 10/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4956807 | 0.99 | MEN1 (0.44) | MEN1MAPTKMT2AMAPK1ROCK1 | |
| SCHEMBL4728299 | 0.93 | ROCK1 (0.44) | MAPK1ROCK1ROCK2RAB9AGCK | |
| SCHEMBL4780576 | 0.88 | ROCK1 (0.55) | MAPTROCK1ROCK2RAB9AGCK | |
| Hydrochloric Acid SCHEMBL4776690 | 0.88 | ROCK1 (0.55) | MAPTROCK1ROCK2RAB9AGCK | |
| SCHEMBL4725546 | 0.85 | ROCK1 (0.56) | ROCK1ROCK2RAB9AGCK | |
| SCHEMBL4725532 | 0.85 | MEN1 (0.46) | MEN1MAPTKMT2AMAPK1ROCK1 | |
| Hydrochloric Acid SCHEMBL4961454 | 0.85 | ROCK1 (0.55) | ROCK1ROCK2RAB9AGCK | |
| SCHEMBL4957984 | 0.84 | ENPP2 (0.46) | MAPK1ROCK1ROCK2GCKENPP2 | |
| Hydrochloric Acid SCHEMBL4845630 | 0.84 | ENPP2 (0.46) | MAPK1ROCK1ROCK2GCKENPP2 | |
| SCHEMBL4776684 | 0.83 | ROCK1 (0.42) | MAPK1ROCK1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716320-B2 | Antibacteriall heterocyclic ureas | REPLIDYNE, INC. (US) | 2014-05-06 | — | — | US | claimed |
| US-20080207703-A1 | Antibacterial heterocyclic ureas | REPLIDYNE, INC. (US) | 2008-08-28 | — | — | US | claimed |
| WO-2008011191-A1 | ANTIBACTERIAL HETEROCYCLIC UREAS | REPLIDYNE, INC. (US) | 2008-01-24 | — | — | WO | claimed |
| US-8716320-B2 | Antibacteriall heterocyclic ureas | REPLIDYNE, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-20080207703-A1 | Antibacterial heterocyclic ureas | REPLIDYNE, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| WO-2008011191-A1 | ANTIBACTERIAL HETEROCYCLIC UREAS | REPLIDYNE, INC. (US) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207703-A1 | Antibacterial heterocyclic ureas | UMPS, UROD, UGP2 | MEN1 2838/4885MAPT 2119/4885KMT2A 3349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.