Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.74 |
| ▸ | RAB9A | P51151 | 10/20 | 0.74 |
| ▸ | NPC1 | O15118 | 9/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.74 |
| ▸ | HPGD | P15428 | 7/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.74 |
| ▸ | RELA | Q04206 | 1/20 | 0.74 |
| ▸ | OGT | O15294 | 1/20 | 0.60 |
| ▸ | UTRN | P46939 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727599 | 0.82 | ALDH1A1 (0.67) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL2127866 | 0.81 | NPC1 (0.76) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL4725022 | 0.81 | NPC1 (0.76) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL2139226 | 0.81 | ALDH1A1 (0.58) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL2127935 | 0.79 | RAB9A (0.69) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL1691846 | 0.78 | NPC1 (0.68) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL29479625 | 0.78 | KDM4E (0.67) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL28695262 | 0.78 | KDM4E (0.67) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL1494782 | 0.78 | KDM4E (0.75) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL27921746 | 0.77 | NPC1 (0.76) | ALDH1A1RAB9ANPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029152-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |