Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 11/20 | 1.00 |
| ▸ | RORC | P51449 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728842 | 0.91 | NPY5R (0.83) | NPY5RRORCMAPTKDM4ELMNA | |
| SCHEMBL6169562 | 0.89 | NPY5R (1.00) | NPY5RRORCMAPTKDM4ELMNA | |
| SCHEMBL7963351 | 0.89 | NPY5R (1.00) | NPY5RRORCMAPTKDM4ELMNA | |
| SCHEMBL4728615 | 0.88 | NPY5R (0.78) | NPY5RRORCMAPTKDM4ELMNA | |
| SCHEMBL4725265 | 0.84 | NPY5R (0.72) | NPY5RMAPTKDM4ELMNAMEN1 | |
| SCHEMBL4725180 | 0.83 | NPY5R (0.71) | NPY5RRORCMAPTKDM4ELMNA | |
| SCHEMBL14199692 | 0.83 | MAPT (0.82) | NPY5RRORCMAPTKDM4ELMNA | |
| SCHEMBL7977234 | 0.81 | NPY5R (0.71) | NPY5RMAPTKDM4ELMNAMEN1 | |
| SCHEMBL4730104 | 0.81 | NPY5R (0.67) | NPY5RRORCMAPTKDM4ELMNA | |
| SCHEMBL4863449 | 0.81 | MAPT (0.79) | NPY5RRORCMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| US-6399631-B1 | 3-AMIDO OR 3-SULFONAMIDO; EATING DISORDERS IN HUMANS, DOGS AND CATS | PFIZER INC. | 2002-06-04 | — | — | US | disclosed |