Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.67 |
| ▸ | RORC | P51449 | 3/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728842 | 0.90 | NPY5R (0.83) | NPY5RRORCMAPTMEN1KMT2A | |
| SCHEMBL4728971 | 0.87 | KDM4E (0.64) | NPY5RRORCMAPTMEN1KMT2A | |
| SCHEMBL4728967 | 0.87 | KDM4E (0.64) | NPY5RRORCMAPTMEN1KMT2A | |
| SCHEMBL4729139 | 0.87 | NPY5R (0.64) | NPY5RRORCMAPTMEN1KMT2A | |
| SCHEMBL4729244 | 0.85 | NPSR1 (0.76) | NPY5RRORCMAPTMEN1KMT2A | |
| SCHEMBL4728749 | 0.85 | NPY5R (0.78) | NPY5RRORCMAPTMEN1KMT2A | |
| SCHEMBL4728698 | 0.85 | MAPT (0.64) | NPY5RRORCMAPTMEN1KMT2A | |
| SCHEMBL4730385 | 0.84 | HDAC6 (0.59) | NPY5RHDAC6MAPTMEN1KMT2A | |
| SCHEMBL4725134 | 0.82 | MAPT (0.77) | NPY5RRORCMAPTMEN1KMT2A | |
| SCHEMBL4726596 | 0.81 | NPY5R (1.00) | NPY5RRORCMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |