Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369697 | 1.00 | KMT2A (0.68) | KMT2AMEN1HPGDCASP3ESR1 | |
| SCHEMBL3870839 | 0.83 | ALDH1A1 (0.66) | KMT2AMEN1HPGDCASP3MMP13 | |
| SCHEMBL17946340 | 0.83 | KMT2A (0.67) | KMT2AMEN1HPGDCASP3MMP13 | |
| SCHEMBL18669025 | 0.82 | CASP3 (0.62) | KMT2AMEN1HPGDCASP3HDAC1 | |
| SCHEMBL13318343 | 0.82 | KMT2A (0.66) | KMT2AMEN1HPGDCASP3MMP13 | |
| SCHEMBL326305 | 0.82 | CASP3 (0.85) | KMT2AMEN1HPGDCASP3HDAC1 | |
| SCHEMBL30472950 | 0.82 | CASP3 (0.85) | KMT2AMEN1HPGDCASP3HDAC1 | |
| SCHEMBL28350022 | 0.81 | KMT2A (0.65) | KMT2AMEN1HPGDCASP3MMP13 | |
| SCHEMBL30378020 | 0.81 | KMT2A (0.65) | KMT2AMEN1HPGDCASP3MMP13 | |
| SCHEMBL135631 | 0.81 | KMT2A (0.51) | KMT2AMEN1HPGDCASP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| CN-1023752-C | Diphenyl ether herbicides | SHELL INT RESEARCH (NL) | 1994-02-16 | — | — | CN | disclosed |
| EP-0145078-B1 | DIPHENYL ETHER HERBICIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-10-12 | — | — | EP | disclosed |
| CN-85101141-A | DIPHENYL ETHER HERBICIDES | — | 1986-10-08 | — | — | CN | disclosed |