SCHEMBL4726727

SCHEMBL4726727

CNS(=O)(=O)c1c[c]n(-c2ncccc2Cl)n1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.38
FTO Q9C0B1 1/20 0.36
SLC40A1 Q9NP59 4/20 0.34
MALT1 Q9UDY8 2/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NFE2L2 Q16236 2/20 0.32
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL535373 0.85 HSD11B1 (0.40) HSD11B1MALT1NFE2L2TRPA1
SCHEMBL535570 0.83 HSD11B1 (0.38) HSD11B1NFE2L2TRPA1
SCHEMBL535280 0.83 HSD11B1 (0.38) HSD11B1NFE2L2TRPA1
SCHEMBL535487 0.82 HSD11B1 (0.38) HSD11B1NFE2L2TRPA1
SCHEMBL535921 0.75 HSD11B1 (0.41) HSD11B1MALT1NPC1RAB9ATRPA1
SCHEMBL536052 0.74 TRPA1 (0.35) HSD11B1MALT1TRPA1
SCHEMBL535531 0.74 HSD11B1 (0.33) HSD11B1MALT1SMN1; SMN2TRPA1
SCHEMBL535632 0.73 TRPA1 (0.37) HSD11B1MALT1SMN1; SMN2TRPA1
SCHEMBL536183 0.72 TRPA1 (0.34) HSD11B1MALT1TRPA1
SCHEMBL536083 0.72 TRPA1 (0.34) HSD11B1MALT1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed