Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726147 | 0.92 | HPGD (0.55) | ALDH1A1HPGDNPY5RMEN1KMT2A | |
| Thiosemicarbazide SCHEMBL28054001 | 0.88 | ALDH1A1 (0.55) | ALDH1A1HPGDNPY5RMEN1KMT2A | |
| SCHEMBL4726929 | 0.88 | KDM4E (0.69) | ALDH1A1HPGDNPY5RMEN1KMT2A | |
| SCHEMBL29643278 | 0.88 | MEN1 (0.55) | ALDH1A1HPGDNPY5RMEN1KMT2A | |
| SCHEMBL4727525 | 0.88 | MEN1 (0.55) | ALDH1A1HPGDNPY5RMEN1KMT2A | |
| SCHEMBL2026269 | 0.82 | KDM4E (0.76) | ALDH1A1HPGDNPY5RMEN1KMT2A | |
| SCHEMBL1594119 | 0.81 | NPY5R (0.72) | NPY5RMEN1KMT2ARORCKDM4E | |
| SCHEMBL4728742 | 0.80 | PTGER4 (0.62) | ALDH1A1HPGDNPY5RMEN1KMT2A | |
| SCHEMBL4727039 | 0.80 | MEN1 (0.50) | ALDH1A1HPGDNPY5RMEN1KMT2A | |
| SCHEMBL31003467 | 0.79 | RORC (0.47) | ALDH1A1HPGDNPY5RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418484-A | Preparation method of 3-formyl(acetyl)-N-alkyl carbazole semicarbazide (thiosemicarbazide) Schiff base | UNIV SHAANXI SCIENCE & TECH | 2016-03-23 | — | — | CN | disclosed |
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |