Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725291 | 0.83 | GFER (0.50) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4024926 | 0.76 | MEN1 (0.74) | MAPTTHRBMEN1KMT2ANPC1 | |
| SCHEMBL30523171 | 0.76 | MEN1 (0.74) | MAPTTHRBMEN1KMT2ANPC1 | |
| SCHEMBL6688877 | 0.75 | MAPT (0.50) | MAPTTHRBMEN1KMT2ANPC1 | |
| SCHEMBL9623026 | 0.74 | USP2 (0.47) | MAPTTHRBMEN1KMT2ANPC1 | |
| SCHEMBL4022771 | 0.74 | MAPT (0.48) | MAPTTHRBMEN1KMT2ANPC1 | |
| SCHEMBL7020838 | 0.74 | AR (0.51) | MAPTMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL2485234 | 0.73 | MAPT (0.61) | MAPTTHRBMEN1KMT2ANPC1 | |
| SCHEMBL6688391 | 0.72 | MAPT (0.60) | MAPTTHRBMEN1KMT2ANPC1 | |
| SCHEMBL31147105 | 0.71 | CA1 (0.54) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |