Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726736 | 0.83 | MAPT (0.46) | GFERMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7020838 | 0.78 | AR (0.51) | GFERMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11742170 | 0.77 | GFER (0.61) | GFERMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29643236 | 0.73 | MAPT (0.70) | GFERMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1586929 | 0.73 | MAPT (0.70) | GFERMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10738593 | 0.72 | MAPT (0.68) | GFERMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9623152 | 0.71 | GFER (0.48) | GFERMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4783201 | 0.71 | MAPT (0.40) | GFERMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4029984 | 0.71 | GFER (0.50) | GFERMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6691691 | 0.71 | GFER (0.61) | GFERMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |