SCHEMBL4726804

SCHEMBL4726804

CCC(Oc1ccc(/C(C)=N/OCc2ccccc2F)cc1C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARG P37231 16/20 0.46
PPARA Q07869 16/20 0.46
PPARD Q03181 2/20 0.44
S1PR1 P21453 1/20 0.41
MAOB P27338 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4726805 1.00 PPARG (0.46) PPARGPPARAPPARDS1PR1MAOB
SCHEMBL4782968 0.87 PPARA (0.41) PPARGPPARAPPARDMAOBSMN1; SMN2
SCHEMBL4782973 0.87 PPARA (0.41) PPARGPPARAPPARDMAOBSMN1; SMN2
SCHEMBL4782977 0.84 PPARA (0.40) PPARGPPARAPPARDSMN1; SMN2
SCHEMBL4726944 0.82 PPARG (0.63) PPARGPPARAPPARDS1PR1MAOB
SCHEMBL4728590 0.80 PPARA (0.60) PPARGPPARAPPARDS1PR1
SCHEMBL4728569 0.79 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL4728564 0.79 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL4729759 0.79 PPARA (0.41) PPARGPPARAPPARDSMN1; SMN2
SCHEMBL4728606 0.77 SAE1 (0.44) PPARGPPARAPPARDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed