SCHEMBL4782977

SCHEMBL4782977

CCC(Oc1ccc(CC(=NOCc2ccccc2F)c2ccccc2)cc1C)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 13/20 0.40
PPARG P37231 12/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
PTPN1 P18031 2/20 0.37
PTPN2 P17706 1/20 0.37
CDC25B P30305 1/20 0.37
FFAR4 Q5NUL3 1/20 0.36
PPARD Q03181 2/20 0.36
CD274 Q9NZQ7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4782968 0.92 PPARA (0.41) PPARAPPARGSMN1; SMN2PPARD
SCHEMBL4782973 0.92 PPARA (0.41) PPARAPPARGSMN1; SMN2PPARD
SCHEMBL4727843 0.84 PPARA (0.51) PPARAPPARGSMN1; SMN2FFAR4PPARD
SCHEMBL4726805 0.84 PPARG (0.46) PPARAPPARGSMN1; SMN2PPARD
SCHEMBL4726804 0.84 PPARG (0.46) PPARAPPARGSMN1; SMN2PPARD
SCHEMBL4725597 0.83 PPARD (0.45) PPARAPPARGFFAR4PPARD
SCHEMBL4729759 0.82 PPARA (0.41) PPARAPPARGSMN1; SMN2PTPN1PTPN2
SCHEMBL4729733 0.81 PPARA (0.48) PPARAPPARGSMN1; SMN2FFAR4PPARD
SCHEMBL4727900 0.78 PPARG (0.53) PPARAPPARGPPARD
SCHEMBL4727840 0.78 PPARA (0.49) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed