SCHEMBL4729759

SCHEMBL4729759

CCC(Oc1ccc(CC=NOCc2ccccc2F)cc1C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 8/20 0.41
PPARG P37231 7/20 0.41
SMN1; SMN2 Q16637 1/20 0.37
FFAR4 Q5NUL3 3/20 0.37
PPARD Q03181 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
AKR1C3 P42330 1/20 0.35
PTPN1 P18031 3/20 0.35
PTPN2 P17706 2/20 0.35
CDC25B P30305 2/20 0.35
FFAR1 O14842 1/20 0.35
MMP1 P03956 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4726950 0.82 LTB4R (0.44) PPARAPPARGFFAR4PPARDALDH1A1
SCHEMBL4782977 0.82 PPARA (0.40) PPARAPPARGSMN1; SMN2FFAR4PPARD
SCHEMBL4728593 0.82 PPARA (0.48) PPARAPPARGSMN1; SMN2FFAR4PPARD
SCHEMBL4730644 0.80 PPARG (0.53) PPARAPPARGPPARDFFAR1
SCHEMBL4726804 0.79 PPARG (0.46) PPARAPPARGSMN1; SMN2PPARD
SCHEMBL4726805 0.79 PPARG (0.46) PPARAPPARGSMN1; SMN2PPARD
SCHEMBL4728913 0.78 PPARA (0.51) PPARAPPARGSMN1; SMN2FFAR4PPARD
SCHEMBL4782973 0.78 PPARA (0.41) PPARAPPARGSMN1; SMN2PPARD
SCHEMBL4782968 0.78 PPARA (0.41) PPARAPPARGSMN1; SMN2PPARD
SCHEMBL4728611 0.77 HDAC6 (0.40) PPARAPPARGSMN1; SMN2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed