Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260648 | 0.96 | CA12 (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4603618 | 0.96 | CA12 (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL500878 | 0.96 | CA12 (0.48) | CA12CA1CA2CA9CA14 | |
| Potassium Ion SCHEMBL472611 | 0.96 | CA12 (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL3683752 | 0.96 | CA12 (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4604488 | 0.96 | CA12 (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL500730 | 0.96 | CA12 (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL9556912 | 0.93 | CA12 (0.46) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4655372 | 0.90 | KDM4E (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6394369 | 0.84 | TSHR (0.47) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554330-B1 | PARTIALLY ESTER-EXCHANGED SIPM AND PROCESS THEREWITH | INVISTA TECH SARL (CH) | 2009-03-11 | — | — | EP | claimed |
| EP-1572818-B1 | SELF-CROSSLINKING AQUEOUS ACETOACETATE-FUNCTIONALIZED SULFONATED ALKYD SYSTEMS | EASTMAN CHEM CO (US) | 2006-06-07 | — | — | EP | claimed |
| JP-2006511669-A | — | — | 2006-04-06 | — | — | JP | claimed |
| EP-1572818-A1 | SELF-CROSSLINKING AQUEOUS ACETOACETATE-FUNCTIONALIZED SULFONATED ALKYD SYSTEMS | EASTMAN CHEMICAL COMPANY (US) | 2005-09-14 | — | — | EP | claimed |
| EP-1554330-A1 | PARTIALLY ESTER-EXCHANGED SIPM AND PROCESS THEREWITH | INVISTA Technologies S.à.r.l. (US) | 2005-07-20 | — | — | EP | claimed |
| US-20040242838-A1 | Sulfonated polyester and process therewith | DUAN JIWEN F (US) | 2004-12-02 | — | — | US | claimed |
| WO-2004061026-A1 | SELF-CROSSLINKING AQUEOUS ACETOACETATE-FUNCTIONALIZED SULFONATED ALKYD SYSTEMS | EASTMAN CHEMICAL COMPANY (US) | 2004-07-22 | — | — | WO | claimed |
| US-6706852-B2 | Partially ester-exchanged SIPM and process therewith | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-03-16 | — | — | US | claimed |
| US-6683132-B1 | COATING COMPRISING MONOFUNCTIONAL CYCLOALIPHATIC SECONDARY AMINE AND POLYFUNCTIONAL PRIMARY AMINE; ADHESIVES, INKS, PRIMERS, AND OVERPRINT VARNISHES | EASTMAN CHEMICAL COMPANY | 2004-01-27 | — | — | US | claimed |
| WO-2004005370-A1 | PARTIALLY ESTER-EXCHANGED SIPM AND PROCESS THEREWITH | INVISTA TECHNOLOGIES S.À.R.L. (US) | 2004-01-15 | — | — | WO | claimed |
| US-5378757-A | Containing sulfonate groups | EASTMAN CHEMICAL COMPANY (US) | 1995-01-03 | — | — | US | claimed |
| EP-0364331-B1 | Water-dissipatable polyester resins and coatings prepared therefrom | EASTMAN KODAK CO (US) | 1994-06-08 | — | — | EP | claimed |
| US-4990593-A | Curable with amino resin; waterproof enamel; polyesteramides from aminocarboxylic acids, amino alcohols, sulfonated acids, glycols, diamines | EASTMAN KODAK COMPANY (US) | 1991-02-05 | — | — | US | claimed |
| EP-0409916-A1 | WATER-DISSIPATABLE POLYESTER RESINS AND COATINGS PREPARED THEREFROM | EASTMAN KODAK COMPANY (US) | 1991-01-30 | — | — | EP | claimed |
| WO-1990003994-A2 | WATER-DISSIPATABLE POLYESTER RESINS AND COATINGS PREPARED THEREFROM | EASTMAN KODAK COMPANY (US) | 1990-04-19 | — | — | WO | claimed |
| EP-0364331-A2 | Water-dissipatable polyester resins and coatings prepared therefrom | EASTMAN CHEMICAL COMPANY (US) | 1990-04-18 | — | — | EP | claimed |
| US-4910292-A | Having carbonyloxy linking groups | EASTMAN KODAK COMPANY (US) | 1990-03-20 | — | — | US | claimed |
| EP-0073437-B1 | DYED POLYESTER FIBER COMPOSITE STRUCTURE | TEIJIN LIMITED (JP) | 1987-05-20 | — | — | EP | claimed |
| US-4468434-A | COATINGS, BRILLIANCE, POROSITY | TEIJIN LIMITED (JP) | 1984-08-28 | — | — | US | claimed |
| EP-0073437-A2 | Dyed polyester fiber composite structure | TEIJIN LIMITED (JP) | 1983-03-09 | — | — | EP | claimed |