Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 5/20 | 0.43 |
| ▸ | CA1 known ✓ | P00915 | 5/20 | 0.43 |
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.43 |
| ▸ | XDH known ✓ | P47989 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260648 | 0.93 | CA12 (0.48) | KDM4ECA12CA1CA2CA9 | |
| Potassium Ion SCHEMBL472611 | 0.90 | CA12 (0.48) | KDM4ECA12CA1CA2CA9 | |
| Lithium Ion SCHEMBL472702 | 0.90 | CA12 (0.48) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL500730 | 0.90 | CA12 (0.48) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL4603618 | 0.90 | CA12 (0.48) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL500878 | 0.90 | CA12 (0.48) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL4604488 | 0.90 | CA12 (0.48) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL3683752 | 0.90 | CA12 (0.48) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL1331221 | 0.87 | LCK (0.47) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL9556912 | 0.86 | CA12 (0.46) | KDM4ECA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57143323-A | — | — | None | — | — | JP | disclosed |
| EP-1574608-B1 | POLYESTER FALSE-TWISTED YARN AND METHOD OF MANUFACTURING THE YARN | TEIJIN LTD (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-7000375-B2 | Polyester false-twist yarn and method of manufacturing the yarn | TEIJIN LIMITED (JP) | 2006-02-21 | — | — | US | disclosed |
| EP-1574608-A1 | POLYESTER FALSE-TWISTED YARN AND METHOD OF MANUFACTURING THE YARN | TEIJIN LIMITED (JP) | 2005-09-14 | — | — | EP | disclosed |
| US-20050102992-A1 | Polyester false-twist yarn and method of manufacturing the yarn | TEIJIN FRONTIER CO., LTD. (JP) | 2005-05-19 | — | — | US | disclosed |
| JP-S57143323-A | PREPARATION OF POLYESTER | TEIJIN LTD | 1982-09-04 | — | — | JP | disclosed |