SCHEMBL260648

SCHEMBL260648

COC(=O)c1cc(C(=O)OC)cc(S(=O)(=O)[O-])c1.[Na+]

nearest known ligand 0.48

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 known ✓ O43570 5/20 0.48
CA1 known ✓ P00915 5/20 0.48
CA2 known ✓ P00918 5/20 0.48
XDH known ✓ P47989 1/20 0.47
CA9 Q16790 5/20 0.48
CA14 Q9ULX7 4/20 0.48
CA7 P43166 1/20 0.48
KDM4E B2RXH2 4/20 0.48
POLB P06746 3/20 0.47
GAA P10253 2/20 0.47
LMNA P02545 1/20 0.47
NFKB1 P19838 1/20 0.47
GFER P55789 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
FUT7 Q11130 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 5/20 0.44
FBP1 P09467 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL500878 0.96 CA12 (0.48) CA12CA1CA2CA9CA14
SCHEMBL4603618 0.96 CA12 (0.48) CA12CA1CA2CA9CA14
SCHEMBL500730 0.96 CA12 (0.48) CA12CA1CA2CA9CA14
Lithium Ion SCHEMBL472702 0.96 CA12 (0.48) CA12CA1CA2CA9CA14
SCHEMBL3683752 0.96 CA12 (0.48) CA12CA1CA2CA9CA14
Potassium Ion SCHEMBL472611 0.96 CA12 (0.48) CA12CA1CA2CA9CA14
SCHEMBL4604488 0.96 CA12 (0.48) CA12CA1CA2CA9CA14
SCHEMBL4655372 0.93 KDM4E (0.43) CA12CA1CA2CA9CA14
SCHEMBL9556912 0.93 CA12 (0.46) CA12CA1CA2CA9CA14
SCHEMBL2469841 0.86 KDM4E (0.39) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630710-B1 1,5-pentanediol-based polyester compositions with enhanced crystallization rates and methods of manufacture THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2026-05-19 US claimed
US-20260125512-A1 WATER SOLUBLE CO-POLYESTER ESTER INDUSTRIES LTD (IN) 2026-05-07 US claimed
US-20260051614-A1 BATTERY SEPARATORS AND METHODS OF MAKING THE SAME MAGNERA CORP (US) 2026-02-19 US claimed
US-12460159-B2 Aqueous polyester compositions, detergents, and cleaning agents containing them and their use CATEXEL GMBH (DE) 2025-11-04 US claimed
EP-4612207-A1 POLYESTERS CLARIANT INTERNATIONAL LTD (CH) 2025-09-10 EP claimed
EP-4612212-A1 POLYESTERS CLARIANT INTERNATIONAL LTD (CH) 2025-09-10 EP claimed
EP-4612208-A1 POLYESTERS CLARIANT INTERNATIONAL LTD (CH) 2025-09-10 EP claimed
EP-4514898-A1 WATER SOLUBLE CO-POLYESTER Ester Industries Limited (IN) 2025-03-05 EP claimed
WO-2024171227-A1 WATER SOLUBLE CO-POLYESTER ESTER INDUSTRIES LIMITED (IN) 2024-08-22 WO claimed
CN-118459955-A High-crystallization-temperature polyester material based on in-situ nucleation and preparation method thereof 山西智创高聚新材料研究院有限公司 2024-08-09 CN claimed
US-4940560-A MELT SPINNING, THERMOPLASTIC RESIN, POLYOXYALKYLENE GLYCOLS TOYO BOSEKI KABUSHIKI KAISHA (JP) 1990-07-10 US claimed
EP-0122623-B1 ANTISTATIC FIBER AND ITS PRODUCTION Toyo Boseki Kabushiki Kaisha (JP) 1989-07-19 EP claimed
EP-0119882-B1 SIZING COMPOSITION, ITS PREPARATION AND ITS USE IN THE SIZING OF TEXTILE THREADS RHONE-POULENC CHIMIE (FR) 1986-11-05 EP claimed
US-4600743-A THERMOPLASTIC RESINS;MELT SPINNING TOYO BOSEKI KABUSHIKI KAISHA (JP) 1986-07-15 US claimed
US-4551382-A POLYESTERURETHANE AND ACRYLIC OR VINYL POLYMER RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-11-05 US claimed
US-4539366-A POLYESTERURETHANE COPOLYMER AND ACRYLIC AND/OR VINYL POLYMER BLEND RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-09-03 US claimed
EP-0122623-A2 Antistatic fiber and its production Toyo Boseki Kabushiki Kaisha (JP) 1984-10-24 EP claimed
US-4241170-A PHOTOGRAPHIC FILMS WITH GOOD PERMEABILITY TO WATER VAPOR CONTAINING AN ALKALI METAL SALT OF A SULFONIC ACID SUBSTITUTED DICARBOXYLIC ACID ESTER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-12-23 US claimed
US-4217441-A FROM GLYCOL DIESTER OF A DICARBOXYLIC ACID, POLYETHYLENE GLYCOL, AND ALKALI SULFONATE-SUBSTITUTED DIESTER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-08-12 US claimed
US-4076783-A DYEABILITY, MELT SPINNING, ORIENTATION, SULFONATE GROUPS TOYOBO CO., LTD. (JA) 1978-02-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125512-A1 WATER SOLUBLE CO-POLYESTER MIF, SMURF1, SLC16A7 CA12 374/4885CA1 81/4885CA2 719/4885
US-12630710-B1 1,5-pentanediol-based polyester compositions with enhanced crystallization rates and methods of manufacture GRIN2D, SMCHD1, GRIN2C CA12 317/4885CA1 14/4885CA2 55/4885
US-20260051614-A1 BATTERY SEPARATORS AND METHODS OF MAKING THE SAME NCL, NUCB2, MCM4 CA12 1442/4885CA1 1175/4885CA2 1725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.