Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694237 | 0.80 | EP300 (0.34) | NOTUM | |
| SCHEMBL28449256 | 0.79 | SMN1; SMN2 (0.34) | NOTUM | |
| SCHEMBL1033158 | 0.72 | — | — | |
| SCHEMBL5694084 | 0.67 | DNMT1 (0.37) | NOTUM | |
| SCHEMBL21186 | 0.67 | NOTUM (0.43) | NOTUM | |
| SCHEMBL2519583 | 0.67 | IKBKB (0.32) | — | |
| SCHEMBL27696561 | 0.66 | EP300 (0.36) | — | |
| Methane SCHEMBL27916787 | 0.66 | NOTUM (0.42) | NOTUM | |
| SCHEMBL27740855 | 0.64 | NOTUM (0.41) | NOTUM | |
| SCHEMBL27798766 | 0.62 | ALB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356165-A | Process for preparing gemcitabine and related intermediates | CHEMAGIS LTD (IL) | 2009-01-28 | — | — | CN | claimed |
| CN-101356165-A | Process for preparing gemcitabine and related intermediates | CHEMAGIS LTD (IL) | 2009-01-28 | — | — | CN | disclosed |
| WO-2008026222-A2 | PROCESS AND INTERMEDIATES OF 2,2' DIFLUORONUCLEOSIDES | SHILPA MEDICARE LTD (IN) | 2008-03-06 | — | — | WO | disclosed |
| EP-0732338-B1 | 2,2-Difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides | LILLY CO ELI (US) | 2002-05-15 | — | — | EP | disclosed |
| EP-0732338-A1 | 2,2-Difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides | ELI LILLY AND COMPANY (US) | 1996-09-18 | — | — | EP | disclosed |
| US-5521294-A | 2,2-difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides | ELI LILLY AND COMPANY (US) | 1996-05-28 | — | — | US | disclosed |